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Sh-oligopeptide-1

["Peptides","Biotechnology-derived ingredients"]

Sh-oligopeptide-1

Regenerating, healing, rejuvenating

Key Benefits

  • Supports a smoother-looking complexion
  • Helps condition the skin
  • Complements rejuvenating routines
  • Supports the appearance of resilient skin

How It Works

EGF is a signaling protein that binds the epidermal growth factor receptor in biological systems. sh-Oligopeptide-1 is produced through recombinant biotechnology and is included in cosmetics with the aim of supporting signaling associated with epidermal appearance and conditioning.

Intact skin is an effective barrier to large water-soluble proteins, and activity can be affected by dose, stability, packaging, and delivery. For that reason, mechanistic plausibility does not by itself establish meaningful topical results.

Ingredient Details

INCI Name: sh-Oligopeptide-1

Ingredient Type: ["Recombinant peptide","Skin-conditioning peptide"]

Best For

Normal skin · Dry skin · Combination skin · Mature skin

What It Is

A biotechnology-produced human-identical oligopeptide used in cosmetics and commonly associated with epidermal growth factor signaling.

What It Does

Supports skin conditioning and a smoother, revitalized appearance, while the strength of evidence for specific growth-factor effects remains limited.

Sh-oligopeptide-1 FAQs

Common questions about this ingredient in skincare.

What is sh-Oligopeptide-1?
It is a recombinant, human-identical oligopeptide commonly associated with epidermal growth factor and used as a cosmetic skin-conditioning ingredient.
What does the “sh” prefix mean?
In cosmetic naming, “sh” denotes a synthetic human-identical material produced through biotechnology rather than harvested from human tissue.
Does topical EGF penetrate skin?
Penetration through intact skin is a major formulation challenge. Delivery systems and finished-product testing matter, and evidence remains limited.
Can it permanently regenerate skin?
No permanent regeneration claim is established for ordinary cosmetics. It is better understood as a supportive conditioning ingredient.
Can I use it with retinoids or exfoliating acids?
Often yes, but combining multiple actives can increase irritation. Follow product directions and reduce frequency if sensitivity develops.
Who should be cautious?
People with highly reactive skin, active dermatologic conditions, or concerns about growth-factor products should ask a qualified clinician before use.
Shop the ingredient

Products Featuring Sh-oligopeptide-1

elvis+elvin Calendula Lifting Treatment Mask productelvis+elvin Calendula Lifting Treatment Mask product image
Calendula Lifting Treatment Mask
セール価格¥18,000